Mitochondrial Fission and Mitophagy Coordinately Restrict High Glucose Toxicity in Cardiomyocytes
Hyperglycemia-induced mitochondrial dysfunction plays a key role in the pathogenesis sensationnel kiyari of diabetic cardiomyopathy.Injured mitochondrial segments are separated by mitochondrial fission and eliminated by autophagic sequestration and subsequent degradation in the lysosome, a process termed mitophagy.However, it remains poorly underst